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Open the Door to Discovery with LECO

More Annotations, Higher Confidence, Accurate Conclusions

Uncover What’s Beneath the Surface of Your Metabolomics Data

For years, scientists have turned to LECO to deliver the sensitivity and accuracy needed to go beyond the surface of metabolomics. Whether deciphering the intricate metabolic pathways of a disease or exploring new horizons in exposomics, our advanced instruments, streamlined workflows, and innovative software tools are designed to solve the toughest analytical challenges.

Scroll through our application notes, webinars, and featured instruments, to discover how LECO empowers researchers to transform data into groundbreaking insights. Move from research to discovery, faster and more confidently than ever before.

Metabolomics Webinar Series

Unlock Molecular Insights with Our Webinars

Gain a higher level of confidence in your metabolomics analyses by tuning in to our informative webinars. Learn from experts in the field and discover how LECO instruments can help you achieve faster and more reliable results.

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June 17, 2025 | 10:00 am est

Comprehensive Omics Profiling for Volatiles and Uncommon Fatty Acids: from Bees to Microbes

Professor Oliver Fiehn, University of California / Davis

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July 22, 2025 | 11:00 AM EST

Quality Control Approaches for Volatile Molecule Analysis Using GCxGC-HRTOFMS, Case Study for TB Sputum Volatiles

Grant Ochoa, Lead Chemist | PhD, Shirley Diagnostics

Metabolomics Profiling

Browse the app notes below to discover how our mass spectrometers perform when put to the test with your industry’s applications.

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A Comprehensive GC-TOFMS Metabolomics Workflow

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High-Resolution GCxGC for Improved Yeast Metabolite Characterization

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Metabolomic Profiling of Corn and Rice Extracts Using a Benchtop GC-TOFMS

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How Comprehensive is Your Analysis? Human Molecular Profiling Using High Resolution Time-of-Flight Mass Spectrometry

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How Comprehensive is Your Analysis? Human Molecular Profiling Using High Resolution Time-of-Flight Mass Spectrometry

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Application of GC High Resolution Time-of-Flight Mass Spectrometry to Mouse Liver Metabolomic Analyses

The LECO Difference

Trusted expertise, groundbreaking technology, and a commitment to your success.

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Uncover Hidden Insights

Time of Flight mass spec delivers unparalleled non-target data, every chemical feature captured.

LECO maximize annotation accuracy

Maximize Annotation Accuracy

High resolution, accurate mass instruments paired with ionization source flexibility provide analysts every clue to annotate with confidence.

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Discovery, Simplified

End-to-end software solutions can rapidly identify potential biomarkers, monitor metabolism behavior over time, and much more.

Best In Class Service

We dedicate ourselves to your success through unmatched support, training, and fast service.

Featured Instruments and Software

LECO Pegasus BTX

Pegasus BTX

High Sensitivity Time-of-Flight Mass Spectrometer for GC and GCxGC

LECO Pegagsus gc-hrt

Pegasus HRT

High-resolution GC-TOFMS with Folded Flight Path technology

LECO Chroma TOF Sync

ChromaTOF Sync

Visually Compare GCMS data sets

LECO chroma TOF tile

ChromaTOF Tile

Comparison software for GCxGC data

Liverpool Training Centre for Metabolomics

Available Courses

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The Liverpool Training Centre for Metabolomics, in partnership with LECO Corp, provides metabolomics-based training to improve the impact of your research and collaborations.

Liverpool Training Centre for Metabolomics offers a range of courses, from introductory to advanced levels, to support the development of researchers across the biological and clinical sciences. Our vocational-based training is designed to equip you with the knowledge and practical skills needed to apply metabolomics effectively in your own research.

Courses are delivered both online and face-to-face, providing hands-on experience with metabolomics workflows, interpreting results, and translating findings into biological insights. Small group sessions allow you to learn directly from experienced instructors and share knowledge with fellow researchers.

If you’re interested in applying metabolomics in your research, view our available courses via this link. For further information, please contact Dr Cate Winder at C.L.Winder@liverpool.ac.uk.

Testimonials

Ing. Jan Rezek, Ph.D., Inst. of Experimental Botany

“Compared to GC equipped with a single column, the Pegasus 4D enabled me to separate unbelievable number of analytes! Tens of thousands of separated peaks in one run was not an exception. But where the separation was not perfect, ChromaTOF software and its deconvolution algorithm did the job. Such excellent ‘separating power’ helped me discover new types of plant PCB metabolites.
Don’t forget! it is not just a horse. It is a Pegasus! A winged horse! Just let it fly! It shows you separations where you don’t even expect it!

Ing. Jan Rezek, Ph.D., Inst. of Experimental Botany
Czech Academy of Sciences

“Our metabolomics research has utilized a LECO Pegasus 4D for over 15 years. Total downtime has probably been less than 20 days for the entire 15 years. When we do have a problem or even a question about using the instrument, LECO are very swift to respond, resolve the issue and offer support and assistance usually within a day of contacting them, and quite often on the same day. The source has never been cleaned or replaced, and we still have the same detector from the original installation. Multiple papers have been produced using data produced from our LECO and I can honestly say it’s been a great asset to our team at York University.”

David Harvey, Technical Specialist – Metabolite Profiling
CNAP | University of York

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